A mechanical cryogenic freezer is used for the long-term cryopreservation of samples such as cell cultures, tissue samples, bacteria, viruses and non-biological products such as electronics. Applications include cord blood preservation, biobanks, reproductive procedures, blood banks, life science research, biomedical engineering and fisheries. Mechanical cryopreservation is a safe alternative to LN2 and can reduce or eliminate the reliance on LN2, reducing safety concerns.